Climate change could affect South Africa’s water resources, resulting in water-use impacts on its residential, agricultural, and industrial sectors. To help South African farmers adapt to climate change, researchers at the University of the Free State Bloemfontein used an economic model that simulates the impacts of adaptation strategies. The Ceres Dynamic Integrated Model showed significant impact to the farming community, but also demonstrated how adaptation could enhance the welfare of farmers. This modeling effort aligns with adaptation priorities in South Africa’s INDC, particularly measures that emphasize engagement and building capacity at the subnational level to support adaptation. Key actions and good practices aligned with this modeling effort are highlighted below.