Coastal cities like Cartagena are particularly vulnerable to the effects of climate change such as sea level rise, coastal flooding, and disease. Colombia’s Ministry of Environment and Sustainable Development, the Climate and Development Knowledge Network, the Institute of Marine and Coastal Research (INVEMAR), and local authorities developed the concept of integrating climate change adaptation into Cartagena’s land use plan and other planning policies. Between 2011-2012, stakeholders conducted a climate change vulnerability assessment and prepared adaptation guidelines. The guidelines identify how climate change may affect different neighborhoods and environments around the city as well as different socioeconomic groups (e.g. low-income residents, fisherman) and culminates with priority actions and recommendations for adaptation. Notable good practices implemented during this project are highlighted below and profiled in this case study.